Without carnitine, fatty acids cannot easily enter into mitochondria. The acetyl group is used to form acetyl-CoA, the most important middle-man in generating energy from amino acids, fats, and carbohydrates. So it serves as an energy collector of acetyl groups and both nutrients help improve energy production. The acetyl group is also used to make the important brain chemical acetylcholine. Some studies suggest that perhaps acetyl l-carnitine can even act as a neurotransmitter by itself. This nutrient is sometimes abbreviated as ALC or ALCAR.
Benefits are shown for ADD, Alzheimers, Low Mood/Depression and Chronic Fatigue, as well as sexual functioning issues and Neuropathy.
What you may notice after taking a supplement
- Those who take carnitine pills notice an increase in physical energy, but not as much mental energy. Acetyl l-carnitine has a more immediate and noticeable mental effect than carnitine because it crosses into the brain much better and quicker. The mind boosting effect of ALC is often noticed within a few hours, or even within an hour. Most people report feeling mentally sharper, having more mental stamina, having more focus and being more alert. Some find a mild mood enhancement. Although most pills are sold in 500 mg capsules, it is preferred to use smaller amounts such as 200 to 300 mg in the morning, on an empty stomach.
- The effects from this nutrient would be to take acetylcarnitine a few times a month in the morning, usually 300 mg, and within an hour or two you will notice having more focus, sharper vision, and more mentally motivated to get things done. On higher dosages, such as 500 mg or more, you may notice a feeling of overstimulation which is distracting.
Adverse effects, safety, risk, dangers
- Side effects of overstimulation, restlessness, and nausea may occur at dosages greater than 500 mg. Even higher doses may cause insomnia. If you happen to feel nausea, next time just take the acetyl l-carnitine with food or take a lesser dose.
- You can take acetyl-carnitine occasionally at important days when you need to be alert. When you take dose of around 250 mg., watch for over-stimulation, along with headaches. Some people to well with 100 mg. and that works well to help you focus and be alert but without any negative reactions. Some people are very sensitive and require doses of less than 100 mg, whereas others don’t notice an effect unless they take more than 500 mg.